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Year : 2012  |  Volume : 9  |  Issue : 1  |  Page : 86-93

Nonalcoholic fatty liver disease and hepatitis B virus infection

Department of Gastroenterology, S.C.B. Medical College, Cuttack - 753 007, Odisha, India

Correspondence Address:
Shivaram Prasad Singh
Head, Department of Gastroenterology, SCB Medical College, Cuttack - 753 007
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-9747.193290

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Nonalcoholic fatty liver disease [NAFLD] has rapidly emerged as the most common liver disorder not only in developed countries, but also in the developing countries. This entity encompasses a wide variety of liver abnormalities ranging from plain hepatic steatosis through nonalcoholic steatohepatitis [NASH] to cirrhosis of the liver and hepatocellular carcinoma [HCC]. NAFLD is now recognized as the hepatic manifestation of insulin resistance [IR], and an important marker of the metabolic syndrome [MS]. Although a number of advances have been made in elucidating the pathogenetic mechanisms involved in the causation and perpetuation of NAFLD, a great many unanswered questions remain unresolved yet. In view of the involvement of so many different pathways in the pathogenesis, there has always been a speculation regarding the interaction between NAFLD and other liver diseases especially chronic hepatitis C [CHC] and chronic hepatitis B [CHB], because of theubiquitous distribution of NAFLD and its common association with other liver diseases.

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