Hepatitis B Annual

REVIEW ARTICLE
Year
: 2009  |  Volume : 6  |  Issue : 1  |  Page : 131--140

HBeAg negative chronic Hepatitis B: An overview


Mamun-Al-Mahtab1, SM Fazle Akbar2 
1 Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, and Viral Hepatitis Foundation, Bangladesh
2 Department of Medical Sciences, Toshiba General Hospital, Tokyo, Japan

Correspondence Address:
Mamun-Al-Mahtab
Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka
Bangladesh

Over 350 million people worldwide are infected with hepatitis B virus (HBV), and patients with HBeAg-negative chronic hepatitis B constitute a major proportion of this population. Mutant varieties of HBV resulting from mutations in the precore or core promoter region of the viral genome give rise to HBeAg-negative CHB, and these cases must be differentiated from the inactive carrier state. These patients with HBeAg-negative CHB must be managed judiciously and in certain situations kept under close follow-up instead of rushing to treatment. However, this does not mean advocating adoption of a too conservative approach, allowing many to proceed to irreversible and progressive liver disease. This article provides an overview of the management of HBeAg-negative chronic hepatitis B.


How to cite this article:
MA, Fazle Akbar S M. HBeAg negative chronic Hepatitis B: An overview.Hep B Annual 2009;6:131-140


How to cite this URL:
MA, Fazle Akbar S M. HBeAg negative chronic Hepatitis B: An overview. Hep B Annual [serial online] 2009 [cited 2022 Jul 7 ];6:131-140
Available from: https://www.hepatitisbannual.org/article.asp?issn=0972-9747;year=2009;volume=6;issue=1;spage=131;epage=140;aulast=Mamun-Al-Mahtab,;type=0