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2004| January-December | Volume 1 | Issue 1
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REVIEW ARTICLE
HBV and Indian medical and dental students
Shivaram Prasad Singh, Manorama Swain, Indu Bhusan Kar
January-December 2004, 1(1):229-239
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39,452
781
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Hepatitis B Immunization: FAQs
Shivaram Prasad Singh
January-December 2004, 1(1):240-248
[FULL TEXT]
[PDF]
33,205
886
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Approach to the management of an incidentally detected HBsAg carrier
Yogesh Kumar Chawla
January-December 2004, 1(1):210-216
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22,047
1,241
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Epidemiology of hepatitis B virus infection in India
Abhijit Chowdhury
January-December 2004, 1(1):17-24
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19,297
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Hepatitis B associated hepatocellular carcinoma: Epidemiology, diagnosis and treatment
KM Mohandas
January-December 2004, 1(1):140-152
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19,470
1,501
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Hepatitis B virus infection in pregnancy
Narendra Prasad Bohidar
January-December 2004, 1(1):199-209
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18,357
1,196
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Hepatitis B virus infection in children in India
Malathi Sathiyasekaran, VS Sankaranarayanan
January-December 2004, 1(1):72-91
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16,725
1,065
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Prophylaxis of viral hepatitis: A global perspective
Voranush Chongsrisawat, Pantipa Chatchatee, Yong Poovorawan
January-December 2004, 1(1):25-59
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11,184
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Management of HBV infection in decompensated liver disease
Sudeep Khanna, Arun Kumar
January-December 2004, 1(1):153-198
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10,290
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Universal neonatal hepatitis B virus vaccination in India: Why?
Rakesh Aggarwal
January-December 2004, 1(1):60-71
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9,131
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Histopathological scoring of chronic viral hepatitis
Gupta S Datta
January-December 2004, 1(1):92-112
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8,834
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Management of chronic hepatitis due to hepatitis B virus infection
Subrat Kumar Acharya, Yogesh Batra
January-December 2004, 1(1):113-139
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7,278
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Comments on the prevention of hepatitis B infection in India
Baruch S Blumberg
January-December 2004, 1(1):249-255
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Treatment of chronic hepatitis B in HIV patients
Gourdas Choudhuri
January-December 2004, 1(1):217-228
Infection with HIV and HBV often coexist in the same patient as the two viruses share similar modes of transmission. Around 10% of HIV patients are co-infected with HBV. With early diagnosis of HIV infection and effective anti-retroviral treatment leading to improved survival of patients with HIV infection, Hepatitis B related liver disease is emerging as a significant health problem in this group of patients. Acute Hepatitis B tends to become chronic more often in HIV patients (80% vs 10% in HIV uninfected) indicating an immune dysfunction and defective clearance of the virus. Protection against HBV infection should be provided to HIV patients by effective use of Hepatitis B vaccine. Higher and frequent doses may be required in HIV patients as their immune response rates are poor. The response to treatment of CHB with Interferon-alpha in HIV patients is around 0-10%, much less than what is achieved in non-HIV patients. Considering the cost, adverse effects and the poor response with Interferon-alpha, there is lack of optimism vis-a-vis its use in HIV patients. The nucleoside analogue, Lamivudine, has shown promise in this group of patients. Lamivudine is useful in suppressing replication of both HIV and HBV. It has been found to be effective in suppressing HBV replication in 96% of HIV patients with chronic Hepatitis B infection. This was associated with clinical, biochemical and histological improvement in liver function. The dose of Lamivudine required in this special group is higher (300 mg/day), and the duration of treatment is long (until HBe sero-conversion and disappearance of HBV-DNA from blood). Besides, rebound viral replication on discontinuation of treatment and the development of YMDD mutants while on prolonged treatment are major concerns at the moment.
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From Australia antigen to eradication programs
Baruch S Blumberg
January-December 2004, 1(1):10-16
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EDITORIAL
Editorial
Shivaram Prasad Singh, Yogesh Kumar Chawla
January-December 2004, 1(1):7-9
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4,496
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FOREWORD
Foreword
Baruch S Blumberg
January-December 2004, 1(1):5-6
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3,864
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